Topical Fluoride Gel is a professional, high-concentrated topical fluoride agent, containing from 2,425 to 12,500 ppm F (usually around 10,000 ppm F) based on sodium fluoride, acidulated phosphate fluoride or amine fluoride. It is used to help prevent cavities, tooth decay, and gum disease. Fluoride topical can also help strengthen tooth enamel, remove plaque bacteria from teeth and gums, and decrease painful tooth sensitivity. Topical fluorides strengthen teeth already present in the mouth, making them more decay resistant. Topical Fluoride Gel is very effective.